We layout full analysis and predictions for the Ole Miss vs South Carolina CFB matchup. 
NCAAF

Ole Miss vs South Carolina Prediction, Betting Odds, and Our Best Bet

Ole Miss Set to Dominate South Carolina in Week 6 Showdown

Matt Brown

The Ole Miss Rebels will visit the South Carolina Gamecocks this Saturday in a big Week 6 matchup at Williams-Brice Stadium. Obviously, if you want to bet on this game you’re going to want to know the odds and get some insights.

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Ole Miss is favored by 9.5 points, and the over/under is set at 53.5. The Rebels are coming off a pretty decent start, winning four of their five games. South Carolina isn’t far behind at 3-1, hoping to capitalize on the home-field advantage.

Ole Miss Rebels Breakdown

Ole Miss has been an offensive powerhouse this year. For the most part, their success has been through the air, led by Jaxson Dart, who’s completing an impressive 77.4% of his passes with 1,815 yards, 3 touchdowns, and only 2 interceptions. Their receiving duo of Tre Harris and Cayden Lee has racked up over 1,000 yards. That should tell you everything you need to know about this aggressive offense.

On the ground, Henry Parrish Jr. continues to dominate with 489 yards and 8 touchdowns. This fuels a rushing attack that averages 216.8 yards per game. 

Defensively, the Rebels have been nearly impenetrable as well. They’ve given up only 8.4 points per game, thanks to players like Chris Paul Jr. and Princely Umanmielen, who has 3.5 sacks this season.

Ole Miss' offense ranks second in passing yards per game, with nearly 400 yards, and they lead the FBS in first downs, with 144.

They’re efficient and fast-paced, making them one of the toughest offenses to slow down. There’s a reason they’re ranked #12, but even then that might be a bit undervaluing this team.

South Carolina Gamecocks Breakdown

South Carolina has been a bit more inconsistent. They’ve lost to LSU but pulled off a solid win against Akron.

LaNorris Sellers has struggled, completing only 54.7% of his passes with just 2 touchdowns and 2 interceptions. That’s a mediocre performance from a team that usually has stellar QBs.

While not the most dangerous passing attack, the Gamecocks' run game, led by Raheim Sanders, averages nearly 200 yards per game. That’s where they really make their money.

The Gamecocks’ defense, allowing 17 points per game, is led by Nick Emmanwori, with 24 tackles, and Kyle Kennard, who has 5.5 sacks.

While they rank 14th in the FBS for yards allowed per game, they face their toughest test yet against Ole Miss' high-flying offense.

Betting Trends and Insights

Before you load up that bet slip, think about a few of these insights—

  • Ole Miss has covered the spread in four of their last five games as the favorite.

  • South Carolina has covered five of their last eight games when underdogs by 7 or more points, but they’ve struggled in October games, losing their last four.

  • Both teams have seen the UNDER hit often, with Ole Miss' last four games as favorites and four of South Carolina’s last five as underdogs staying under the total.

Those are just a few things to think about, but not necessarily the end-all-be-all, especially on the under bet.

Prediction and Best Bet

Ole Miss is clearly the more talented and complete team.

Their offense is among the best in the nation, and their defense has been lights out.

South Carolina may keep it competitive early, but with Ole Miss’ offensive firepower and the Gamecocks' inconsistency in the passing game, it’s tough to see South Carolina keeping pace for all four quarters.

While South Carolina has been good as a home underdog, they’ve had a shaky October track record. To top that off, Ole Miss' explosive attack should break through the Gamecocks’ defense. South Carolina may hang around early, but the Rebels have too many weapons.

  • BettorsInsider Pick: Ole Miss -9.5. 

Expect Ole Miss to cover the spread, winning comfortably. The under looks like a solid play as well, given both teams’ recent trends and defensive capabilities. Sure, the 53.5 total is up there, but it’s not out of the realm of possibilities with the Rebel offense.

  • Prediction: Ole Miss 31, South Carolina 17.

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